Search results for " resistin"

A new design problem in the formulation of a special moment resisting connection device for preventing local buckling

2021

In the present paper an improved formulation devoted to the optimal design problem of a special moment resisting connection device for steel frames is proposed. This innovative device is called a Limited Resistance Plastic Device (LRPD) and it has been recently proposed and patented by some of the authors. It is thought to be preferably located at the extremes of the beam, connecting the beam end cross section with the relevant column. The typical device is a steel element characterized by symmetry with respect to three orthogonal barycentric planes and constituted by a sequence of three portions with abrupt cross section changes. The main novelty of the present proposal is related to the d…

Retrofitting of Existing Steel MR-Frames by Encasing the Columns

2005

Summary The study concerns the behaviour of steel MR-frames subjected to vertical and lateral forces, not properly designed according to capacity design criteria, and upgraded by means of encasing the steel columns with concrete having different grade. The purpose of the paper is to examine if the proposed technique allows one to adequately increase the lateral stiffness and the resistance of the frames. Pushover analyses on multi-storey frames are performed trough a non-linear calculus program, able to take into account of the second order effects. The behaviour of frames with encased columns was compared with those of the bare frames, highlighting that with the proposed technique it is po…

PROFILO ENDOCRINO, LIVELLI DI ADIPONECTINA, RESISTINA, LEPTINA IN PAZIENTI CON INSUFFICIENZA RENALE CRONICA IN ETA’ EVOLUTIVA

2009

Iterative Optimal Design of Special Moment Resisting Devices for Steel Frames

2021

Abstract The present paper proposes an iterative procedure devoted to reaching the optimal design of an innovative, recently proposed, moment resisting device. This special device, called Limited Resistance Plastic Device (LRPD), can be utilized, as an example, to equip a steel frame when it is required that the frame must be designed to substitute a masonry panel, i.e., it must be characterized by a structural behaviour as close as possible to the one of the replaced masonry wall. This purpose can be reached by designing the relevant frame imposing appropriate constraints on the elastic stiffness and on the limit resistance. The result can be obtained just by ensuring that the elastic stif…

A proposal for improving the elastic behaviour of dogbone

2022

The Reduced Beam Section (RBS) connections are one of the prequalified connections approved by international standards and adopted to improve the seismic behaviour of steel Moment Resisting Frames (MRF) also protecting the joint between beams and columns. This goal is reached by locally reducing the resistance of a selected portion of the beam element by suitably trimming the flanges, to promote in that portion the onset of plastic deformations. In the framework of RBS, the most important typology proposed is the so-called dogbone (DB) connections that are widely diffused in seismic engineering. The essential advantages of DB are related to the protection of the welded cross section between…

ADIPONECTIN, LEPTIN, RESISTIN LEVELS IN CYSTIC FIBROSIS ADOLESCENTS

2012

INTRODUCTION: Patients with Cystic Fibrosis, especially in adolescence, could develop endocrine and metabolic complications, related to nutritional state and chronic inflammation. They develop a progressive decrease in lean body mass correlated with the progression of lung disease. Adipose tissue is involved as well and adipocytokines are a possible link between malnutrition and long term complications. PATIENTS AND METHODS: In 24 Cystic Fibrosis adolescents we studied auxological, nutritional, glycometabolic, endocrine patterns, together with leptin, adiponectin and resistin levels. We selected patients not affected by diabetes, insulin resistance, malnutrition, acute inflammatory states s…

Shear design of high strength concrete beams in MRFs

2019

This paper presents the criteria for the shear design of high strength concrete (HSC) beams in moment resisting frames (MRFs). The formulation of an analytical model is provided for the case of beams with longitudinal reinforcement in the presence of transverse stirrups. The model is of additive type, in the meaning that the shear resistance of the beam is evaluated as the sum of several contributions. In particular, the contribution of concrete, longitudinal rebars, and transversal reinforcement are taken into account. Furthermore, for assessing the concrete contribution, a classical approach is followed, according to which two effects arise in the shear mechanism: the arc and the beam eff…

Insulin resistance in postmenopausal women with metabolic syndrome and the measurements of adiponectin, leptin, resistin, and ghrelin.

2005

Objective: Metabolic syndrome (MBS) is a significant health care problem in postmenopausal women and is driven largely by obesity. We wished to assess the prevalence of insulin resistance (IR), diagnosed using practical methods, and whether several adipocyte factors (adiponectin, leptin, resistin) or the gastric peptide ghrelin, associated with cardiovascular risk, might be abnormal and may relate to IR. Study design: We evaluated 37 obese postmenopausal women with MBS and 34 matched obese premenopausal controls, as well as 14 non-obese premenopausal controls. We measured fasting glucose and insulin, performed 75g 2 hr oral glucose tolerance and intravenous insulin tolerance tests to assess…

An innovative moment resisting steel connection: optimal design formulations, practical applications and experimental tests

2023

This thesis concerns the study of an innovative moment resisting connection device to be adopted in the so-called moment resisting steel frames. Following previous seismic events, such as Northridge in 1994, many steel structures characterized by welded connections between beams and columns experienced extended damages and diffused brittle failures, making the facilities unserviceable and economically disadvantageous to repair. The answers to this problem is represented by a large number of studies, where several proposals for different devices, as well as special technical solutions, are available. However, the main idea developed among all the proposals is represented by the identificatio…

Shear models of Rc-encased steel joist beams in MRFs

2019

This study presents the application of different analytical and finite element (FE) models aimed at predicting the shear resistance of reinforced concrete (RC) and reinforced concrete-encased steel joist (HRCESJ) beams with inclined transversal reinforcement in moment resisting frames (MRFs). In particular, four analytical models are taken into account, two of them specifically conceived for HRCESJ beams in seismic area. The analytical models considered are Eurocode-2 model for the shear strength of RC beams; a variable-inclination stress-field approach; a strut-and-tie additive model and, finally, an analytical formulation in which the shear capacity depends on the number of pairs of incli…